The Painkillers That Could End the Opioid Crisis

Originally shared by Toxic Reverend

The Painkillers That Could End the Opioid Crisis
By Adam Piore, MIT Technology Review,
August 11, 2016
Researchers may soon vanquish our pain without causing addiction and other devastating side effects.
https://www.technologyreview.com/s/602141/the-painkillers-that-could-end-the-opioid-crisis/?set=602145


Quote from the article:

For the last 20 years, Zadina, a researcher at the Tulane School of Medicine and the Southeast Louisiana Veterans Health Care System, has been on the front lines of a battle to defeat an ancient human adversary: physical pain.

Zadina believes he is getting close to decoupling them. Just this past winter, he and his team published a study in Neuropharmacology reporting that they had treated pain in rats without causing the five most common side effects associated with opioids, including increased tolerance, motor impairment, and respiratory depression, which leads to most opioid-related deaths. The next step is to test it in humans.

Result of a person search:
James Zadina, at the Tulane School of Medicine
http://www2.tulane.edu/sse/neuro/faculty/james-zadina.cfm



The published study that the article is about:

Title:
Endomorphin analog analgesics with reduced abuse liability, respiratory depression, motor impairment, tolerance, and glial activation relative to morphine
Authors:
James E. Zadinaa, b, c, d, , , Mark R. Nilgesc, Jenny Morgenweckb, 1, Xing Zhanga, b, Laszlo Hacklera, b, Melita B. Fasolda, b
Publisher:
Neuropharmacology
Date:
Volume 105, June 2016, Pages 215–227
http://www.sciencedirect.com/science/article/pii/S0028390815302203

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Additional Information:
Unrelated to the article and study, but "On Topic" with treating pain:

What are the Best Cannabis Strains for Pain?
By Bailey Rahn, Leafly
https://www.leafly.com/news/strains-products/best-cannabis-strains-for-treating-pain



In related news:>*


Study: Opioid Use Decreases in States that Legalize Medical Marijuana
A new study suggests doctor prescribe medical marijuana in place of opioids.
By Kimberly Leonard | Staff Writer US News Sept. 15, 2016
https://www.usnews.com/news/articles/2016-09-15/study-opioid-use-decreases-in-states-that-legalize-medical-marijuana



Patients Are Ditching Opioid Pills for Weed
Can marijuana help solve the opioid epidemic?
By Sarah Zhang, The Atlantic, February 2, 2017
http://www.infowars.com/patients-are-ditching-opioid-pills-for-weed/



What are the Best Cannabis Strains for Pain?
By Bailey Rahn, Leafly
https://www.leafly.com/news/strains-products/best-cannabis-strains-for-treating-pain
https://www.technologyreview.com/s/602141/the-painkillers-that-could-end-the-opioid-crisis/?set=602145